Stopping cachexia at its source could reverse wasting from cancer

Blocking an immune protein that helps regulate body weight led mice with cancer to gain muscle

An illustrated brain is outlined in blue on a black background. An area of the brain stem at the base of the brain is highlighted in orangy-red. This area is a target for a potential treatment aimed at reversing the wasting that comes along with advanced cancer.

The area postrema, which lies in the medulla oblongata (highlighted in this illustration) in the brain stem, plays a role in cachexia, a wasting disease that affects an estimated 80 percent of people with advanced cancer.

Sebastian Kaulitzki/Science Photo Library/Getty Images Plus

People with advanced cancers often feel like their bodies are wasting away.